Seasonal Influenza Vaccine High Dose Boosting in Solid Organ Transplant Recipients
Status:
Not yet recruiting
Trial end date:
2023-07-01
Target enrollment:
Participant gender:
Summary
In solid organ transplant (SOT) the receipt of influenza vaccine in an influenza season is
associated with decreased disease severity as demonstrated by the presence of pneumonia and
ICU admissions. Different strategies have been assessed to optimize vaccine efficacy and
immunogenicity of the influenza vaccine in the solid organ transplant recipient (SOTR). The
primary objective of the study is to evaluate the immunogenicity of 2 doses of the high dose
influenza vaccine utilizing neutralizing antibody assays. A control group receiving 1 HD
influenza vaccine will be included.