Sciatic Block in Contralateral Limb Phantom and Residual Limb Pain
Status:
Not yet recruiting
Trial end date:
2024-03-01
Target enrollment:
Participant gender:
Summary
Participants with chronic, refractory phantom limb pain (PLP) or residual limb pain (RLP) for
more than 6 months will be enrolled in this clinical trial. Aim: Define the attributable pain
relief and functional improvement in participants with PLP/RLP after contralateral limb
sciatic nerve block. Also, contribute to the basic science understanding of the
crossed-withdraw reflex by demonstrating a known animal model phenomenon in human
participants. Hypothesis: Contralateral limb sciatic nerve anesthetic block with 2% lidocaine
provides immediate clinically meaningful pain reduction, defined as the proportion of
patients with at least 50% improvement in NRS pain score in PLP/RLP when compared to sham.