Overview

Saracatinib and Paclitaxel in Platinum-resistant Ovarian Cancer

Status:
Completed
Trial end date:
2014-01-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to investigate whether the addition of the Src inhibitor saracatinib (AZD0530) to weekly paclitaxel improves efficacy, compared with paclitaxel plus placebo, in patients with relapsed platinum-resistant ovarian cancer. The trial will also determine toxicity and ascertain whether the combination of paclitaxel plus saracatinib should proceed to a phase III trial.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
University College, London
Collaborators:
AstraZeneca
Cancer Research UK
Treatments:
Albumin-Bound Paclitaxel
Paclitaxel
Saracatinib