Safety of Intravenous Thrombolytics in Stroke on Awakening
Status:
Completed
Trial end date:
2015-12-01
Target enrollment:
Participant gender:
Summary
The primary objective of this study is to evaluate the safety of intravenous tissue
plasminogen activator (IV tPA) in patients waking up with symptoms of acute stroke and
presenting to the Emergency Department (ED) within 4.5 hours from awakening, and meeting
standard criteria for treatment with IV tPA for acute stroke.
The hypothesis is that patients that wake up with stroke symptoms may have developed the
stroke at the time of awakening, and may be within the 4.5 hour window if they arrive to the
ED within that time, therefore IV tPA should be safe and effective in this population.