Safety of 24-hour Infusion of ON 01910.Na in Combination With Gemcitabine in Advanced Solid Tumors
Status:
Completed
Trial end date:
2011-07-01
Target enrollment:
Participant gender:
Summary
Treatment of cancer is often more effective when two or more drugs are used together. For
example, when gemcitabine, an approved drug, and ON 01910.Na, a new investigational
anti-cancer drug, are used together to treat cancer cells in laboratory animals, there is
more inhibition of the growth of the cancer cells compared to either drug used by itself.
These results offer promise that gemcitabine and ON 01910.Na could be used to treat cancer in
patients. However, before studies that seek to find out if gemcitabine and ON 01910.Na is an
effective combination in patients can be done, doctors must first know what is largest, safe
dose of ON 01910.Na that can be used in combination with gemcitabine and what is the best
regimen to use. This study is designed to answer that question.