Safety and Tolerability of Dimebon in Patients on Memantine, and Memantine Plus Donepezil

• Status: Completed
• Trial end date: 2010-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the safety and tolerability of dimebon given to Alzheimer's disease patients currently on a stable dose and regimen of memantine or memantine plus donepezil.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Medivation, Inc.
• Treatments: Donepezil; Memantine

Criteria

Inclusion Criteria:

• Alzheimer's disease

• On Memantine

• Caregiver who is willing to accompany the patient to all clinic visits

Exclusion Criteria:

• Unstable medical illnesses or significant hepatic or renal disease

• Other primary psychiatric or neurological disorders