Safety and Tolerability of Chlorquine in Addition to Anti-tuberculosis Therapy
Status:
Recruiting
Trial end date:
2024-01-01
Target enrollment:
Participant gender:
Summary
In vitro and in vivo data show promising results of adjunctive use of Chloroquine to standard
tuberculosis therapy as Chloroquine enhances animicrobial effectiveness against intracellular
MTB. To date, no safety data of the concurrent use of both treatments is availble. In a phase
I trial, the investigators aim to evaluate safety and tolerability of the concurrent use of
Chloroquine and standard anti-TB drug in healthy volunteers.