Overview

Safety and Targeting of Anti-hk2 Antibody in mCRPC

Status:
Recruiting
Trial end date:
2021-12-31
Target enrollment:
Participant gender:
Summary
This is an imaging trial, to develop h11B6 as a therapeutic radiopharmaceutical for men with mCRPC. This imaging study will be conducted to confirm the safety and estimate the mass amount of antibody h11B6, and confirm in vivo tumor targeting of the antibody, using Indium-111 (111In) radiolabeled h11B6 in subjects with advanced prostate cancer. This study will also provide the dosimetric information crucial for Phase 1 therapy.
Phase:
Early Phase 1
Details
Lead Sponsor:
Tomopath Inc.
Collaborators:
Invicro
Janssen Research & Development, LLC
Treatments:
Antibodies
Immunoconjugates
Immunoglobulins