Safety and Immunogenicity of a New Inactivated Poliovirus Vaccine in Infants
Status:
Completed
Trial end date:
2013-05-01
Target enrollment:
Participant gender:
Summary
A new inactivated polio vaccine based on attenuated poliovirus strains was developed to
transfer the technology to manufacturers in low- and middle-income countries. This vaccine
was produced in different dosages and in different formulations. In healthy adults the safety
of the highest dose was comparable to that of the existing inactivated polio vaccine. The
purpose of this trial is to determine the safety of the different dosages and formulations of
the vaccine in infants. The second goal of this study is to analyse the immune response after
three doses in infants.