Safety and Feasibility of Hypertonic Saline Solution After Aneurysmal Subarachnoid Hemorrhage:
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Subarachnoid hemorrhage (SAH) occurs after rupture of cerebral aneurysms. Treatment of SAH
focuses on avoiding medical complications including cerebral vasospasm, which may result in
limited circulation to the brain. Cerebral vasospasm, or thinning of the arteries of the
brain, is a feared complication that could potentially cause stroke and worst outcomes after
SAH. Hypertonic saline (HTS) is a compound that may be used to prevent vasospasm following
SAH by enhancing the circulation in the brain. This study will evaluate if a protocol of
volume expansion with HTS is safe and effective in patients with subarachnoid hemorrhage for
the prevention of cerebral vasospasm.