Safety and Feasibility Study of Dapivirine (TMC120) Vaginal Ring in Belgium
Status:
Completed
Trial end date:
2005-08-01
Target enrollment:
Participant gender:
Summary
This Phase I trial will assess the feasibility of using a vaginal ring to deliver the
candidate microbicide dapivirine (TMC120) for 7 days. The study population will consist of 13
healthy, sexually abstinent women. Safety and tolerability will be assessed through clinical
and laboratory assessments. Feasibility of drug delivery will be assessed by measuring
dapivirine (TMC120) concentrations in vaginal fluids, vaginal and cervical epithelial tissue,
and plasma.