Overview

Safety and Efficacy of Perioperative Remodulin® in Orthotopic Liver Transplant Recipients

Status:
Withdrawn
Trial end date:
2010-06-01
Target enrollment:
Participant gender:
Summary
Patients undergoing orthotopic liver transplant will experience some degree of clinical and/or biochemical hepatic dysfunction. This early injury is known as primary graft dysfunction and varies from minor abnormalities to primary nonfunction. Prostaglandin-class drugs, including prostacyclin and its analogs, could represent an important advance toward the goal of reducing transplant related morbidity, mortality and associated costs by providing these benefits.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
United Therapeutics
Collaborator:
University of Pittsburgh
Treatments:
Treprostinil