Safety and Efficacy of Nonsteroidal Antiinflammatory (NSAI)Drug and Glucocorticoids in Acute Sciatica

• Status: Completed
• Trial end date: 2016-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether anti-inflammatory drugs or glucocorticoids are effective in the treatment of acute sciatica

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Hospital, Grenoble
• Treatments: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Glucocorticoids; Ketoprofen; Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Prednisolone hemisuccinate; Prednisolone phosphate

Criteria

Inclusion Criteria:

• sciatica <8 weeks resistant to all treatments in ambulatory

• Acute low back pain> 48 hours;

• Non-deficit patients;

• Initial VAS> 40/100;

• Consent of patient

• Conflict disco-radicular concordance with the clinical computed tomography scan or magnetic resonance imaging.

• No of contraindications to methylprednisolone, ketoprofen;

• No registration to another protocol;

Exclusion Criteria:

• Pregnant, parturient, lactating mother;

• Diabetic patient;

• Patient with syndrome from narrowing of the lumbar vertebral canal

• Patient with a history of lumbar surgery <1 year;

• Patient with a Cauda equina syndrome or major motor disability;

• Crural neuralgia

• Patient with a deficit;

• Suspicion of sciatica secondary, ie not conflict-related disco-root: infectious neuritis, fracture on spinal bone tumor ...

associated treatment or pathology contra-indicating administration methylprednisolone, ketoprofen.