Safety and Efficacy of Low Dose Hypertonic Saline Solution and High Dose Furosemide for Congestive Heart Failure
Status:
Completed
Trial end date:
2012-01-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to compare high dose furosemide in combination with low volume
hypertonic saline solution (2.4%) with intermittent pulse dose furosemide in patients with
pre treatment kidney function impairment. The hypothesis is that it will provide effective
diuretic response and have a beneficial effect on preservation of renal function as compared
to pulse furosemide in patients with pre-treatment renal impairment (GFR < 60 mL/min).
Phase:
Phase 3
Details
Lead Sponsor:
Aspirus Heart and Vascular Institute-Research and Education