Safety and Efficacy of Intravenous (IV) Dexmedetomidine During Flexible Bronchoscopy and Endobronchial Ultrasound

• Status: Withdrawn
• Trial end date: 2012-07-01
• Target enrollment: 0
• Participant gender: All

Summary

To achieve safe,consistent, continuous sedation using Dexmedetomidine in advaced bronchoscopy procedures that may reduce the need for rapid pain sedative infusion.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Lahey Clinic
• Treatments: Dexmedetomidine

Criteria

Inclusion Criteria:

• Adults between the age of 18 and 85

• Adults scheduled for flexible brochoscopy using EUBS (Endobronchial Ultrasound)

Exclusion Criteria:

• Sever bradycardia (rate < 50) and / or related bradydysrhymias (e.g. advanced heart block)

• Impaired ventricular functions (EF <30%)

• Hypovolemia or hypotension (SBP <90 or MAP- Have GFR less than 15ml/min 1.73m2 or undergoing hemodialysis

• Endstage liver disease.