Overview

Safety & Efficacy of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in LVAD Recipients

Status:
Completed
Trial end date:
2019-08-23
Target enrollment:
Participant gender:
Summary
The main purpose of this research is to determine whether injecting mesenchymal precursor cells (MPC) into the heart during surgery to implant a left ventricular assist device (LVAD) is safe. MPCs are normally present in human bone marrow and have been shown to increase the development of blood vessels and new heart muscle cells in the heart. In addition, this research is being done to test whether injecting the MPCs into the heart is effective in improving heart function.
Phase:
Phase 2
Details
Lead Sponsor:
Annetine Gelijns
Collaborator:
National Heart, Lung, and Blood Institute (NHLBI)