Overview

Safety and Efficacy of HCB101 in Combination With Multiple Agents in Patients With Advanced Solid Tumors

Status:
RECRUITING
Trial end date:
2029-01-01
Target enrollment:
Participant gender:
Summary
This is a non-randomized, open-label, dose-escalation, and dose-expansion Phase Ib/IIa study to evaluate the safety, tolerability, PK profile, and preliminary efficacy of HCB101 in combination therapies in subjects with advanced solid tumors. The trial consists of four cohorts, each including a part I of the dose-escalation phase (Phase Ib) and a part II of the dose-expansion phase (Phase IIa).
Phase:
PHASE1
Details
Lead Sponsor:
FBD Biologics Limited
Treatments:
Albumin-Bound Paclitaxel
Bevacizumab
Capecitabine
Cetuximab
Fluorouracil
Gemcitabine
Irinotecan
Leucovorin
Oxaliplatin
Paclitaxel
pembrolizumab
pertuzumab
Ramucirumab
toripalimab
Trastuzumab