Overview

Safety and Efficacy of Cobicistat-boosted Darunavir in HIV Infected Adults

Status:
Completed
Trial end date:
2015-10-01
Target enrollment:
Participant gender:
Summary
This study is to evaluate the safety and tolerability of cobicistat-boosted darunavir plus two fully active nucleoside analogue reverse transcriptase inhibitors in HIV 1 infected, antiretroviral treatment-naive and treatment-experienced adults with no darunavir (DRV) resistance-associated mutations. After the Week 48 Visit, participants will be given the option to participate in an open-label rollover phase to receive cobicistat and attend visits every 12 weeks until it becomes commercially available, or until Gilead Sciences elects to terminate development of cobicistat.
Phase:
Phase 3
Details
Lead Sponsor:
Gilead Sciences
Collaborator:
Janssen Research & Development, LLC
Treatments:
Cobicistat
Darunavir
Reverse Transcriptase Inhibitors