Safety and Efficacy of Buprenorphine Transdermal System in Subjects With Moderate to Severe Osteoarthritis of Hip or Knee
Status:
Completed
Trial end date:
2004-06-01
Target enrollment:
Participant gender:
Summary
The objective of this study is to demonstrate the effectiveness and tolerability of the
buprenorphine transdermal system (BTDS) (5, 10 and 20) in comparison to placebo transdermal
system in subjects with moderate to severe osteoarthritis pain of the hip and knee currently
treated with oral opioids. The double-blind treatment intervention duration is 4 weeks during
which time supplemental analgesic medication (acetaminophen) will be provided to all subjects
in addition to study drug.