Safety and Efficacy of Adding Intravenous N-acetyl Cysteine in Colon Surgeries
Status:
Completed
Trial end date:
2016-10-15
Target enrollment:
Participant gender:
Summary
The use of antioxidant agents in the prevention or decreasing the severity of postoperative
systemic inflammatory response syndrome after colonic surgeries adopted nowadays. Therefore,
it is of interest to investigate safety and efficacy of administrating short term intravenous
(IV) N acetyl cysteine as add on to l alany l glutamine and total parenteral nutrition on the
marker of oxidative stress malondialdehyde and anti- inflammatory marker tumor necrosis
factor alpha in patients undergoing colonic surgeries through a prospective, randomized,
double blinded, controlled clinical trial