Safety and Efficacy Study of AVI-5126 When Used on Vein Grafts Before Use in Heart by-Pass Graft Surgery (CABG)
Status:
Terminated
Trial end date:
2009-03-01
Target enrollment:
Participant gender:
Summary
For some people who have heart by-pass surgery, the vein that is used to by-pass a blockage
will, after some time, become narrowed and possibly blocked. AVI-5126 blocks a gene that is
believed to be responsible for the events in the blood vessel that cause this narrowing.
Therefore, exposing the vein to AVI-5126 before it is attached to the coronary artery may
result in less problems with these vein grafts later on. This study will determine if this
procedure is both safe and effective.