Safety and Effectiveness of Novel Nitroglycerin Based Catheter Lock Solution
Status:
Completed
Trial end date:
2016-10-01
Target enrollment:
Participant gender:
Summary
The objective of this Phase I/II pilot study is to evaluate the safety and effectiveness of a
non- antibiotic chelator based lock solution that contains nitroglycerin in combination with
sodium citrate and ethanol (NiCE lock solution) for prevention of central line associated
bloodstream infection (CLABSI).
- The primary objective of this study is to evaluate the safety and estimate the rate of
adverse events associated with the NiCE lock solution.
- The second primary objective is to estimate the rate of CLABSI in patients receiving the
NiCE lock solution.