Safety and Effectiveness of Corneal Crosslinking (CXL): Keratoconus and Post-Refractive Ectasia
Status:
Unknown status
Trial end date:
2019-06-01
Target enrollment:
Participant gender:
Summary
This prospective, randomized study is being conducted to evaluate the safety and
effectiveness of corneal cross-linking (CXL) in patients with keratoconus or post-refractive
ectasia (post-LASIK or PRK) utilizing two techniques: the "standard" Epi-Off technique or an
Epi-On technique that utilizes iontophoresis (I-CXL) to deliver the riboflavin to the cornea
without need for removal of the corneal epithelium. Patients will be randomized to receive
CXL treatment with either the Epi-On or Epi-Off technique.