Safety, Tolerability and Pharmacokinetics of Increasing Doses of BIBN 4096 BS in Healthy Male and Female Volunteers
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The objective of the present study was to obtain information about safety, tolerability and
pharmacokinetics of BIBN 4096 BS after oral administration of increasing doses in healthy
male and female volunteers. With respect to pharmacokinetics, it was of particular importance
to investigate whether therapeutic plasma levels (for treatment of migraine) could have been
achieved by oral administration of a BIBN 4096 BS formulation.