Safety Study of Post Tonsillectomy Ibuprofen Use in Adults

• Status: Unknown status
• Trial end date: 2016-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine if ibuprofen use after electrocautery tonsillectomy increases the post-tonsillectomy hemorrhage rate.

Hypothesis: Use of ibuprofen does not increase the post-tonsillectomy hemorrhage rate.

Primary outcome: Rate of tonsillar hemorrhage following adult tonsillectomy in those receiving narcotic pain medications plus ibuprofen compared to those receiving narcotics alone.

Secondary outcome: Determine whether ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), decreases post tonsillectomy pain, narcotic pain medication use, or cost of pain management.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Brooke Army Medical Center
• Collaborators: 59th Medical Wing; Blanchfield Army Community Hospital; Madigan Army Medical Center; Tripler Army Medical Center; Wilford Hall Medical Center
• Treatments: Ibuprofen

Criteria

Inclusion Criteria:

• Adults 18 years old or older

• Scheduled for tonsillectomy

Exclusion Criteria:

• Prisoners

• Pregnancy

• Allergy to ibuprofen

• History of vasculopathy to include Lupus or Wegener's or Disseminated Intravascular Coagulation (DIC)

• Any other bleeding disorder to include Von Willebrand Disease and others

• Active Neoplasm of any kind

• Tonsillectomy in combination with any sleep surgical procedure or palatal procedure