Safety Study of Combining Ultrasound Microbubbles and Chemotherapy to Treat Malignant Neoplasms of Digestive System

• Status: Unknown status
• Trial end date: 2016-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Ultrasonic sonoporation can increase the release of chemotherapeutics, thus increasing the therapeutic effects. The main purpose is to identify the safety of combining ultrasonic microbubbles and chemotherapeutics to treat malignant neoplasms of hepatic metastases from alimentary system and pancreatic carcinoma.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Beijing Cancer Hospital
• Treatments: Gemcitabine

Criteria

Inclusion Criteria:

• Pathological diagnosis of liver metastases from alimentary system and pancreatic carcinoma

• Failed routine chemotherapy

• Neoplasms can be evaluated by imaging

• ECOG《2

Exclusion Criteria:

• Have systematic chemotherapy in 2 weeks

• Be allergic to ultrasonic microbubbles and chemotherapeutics

• Uncontrolled high blood pressure, cardiovascular disease

• Active bleeding

• Have serious mental and psychological disease