Overview

Safety Study of Bevacizumab, Everolimus and LBH589 (BEL) for Advanced Solid Tumors

Status:
Completed
Trial end date:
2012-05-01
Target enrollment:
Participant gender:
Summary
The main purpose of this study is to test the safety of three study drugs, bevacizumab (Avastin™), Everolimus (Afinitor™) and LBH589 (Panobinostat) when they are given together. It is hoped this study drug combination might lead to a greater decrease the in size of the cancer and/or slow down how fast the cancer is growing compared to when these drugs are given alone. Subjects will be enrolled at Duke University Medical Center (DUMC).
Phase:
Phase 1
Details
Lead Sponsor:
Herbert Hurwitz
Collaborators:
Genentech, Inc.
Novartis
Treatments:
Bevacizumab
Everolimus
Panobinostat
Sirolimus