Safety Study of Adult Mesenchymal Stem Cells (MSC) to Treat Acute Myocardial Infarction

• Status: Completed
• Trial end date: 0000-00-00
• Target enrollment: 53
• Participant gender: Both

Summary

The purpose of the study is to determine whether adult stem cells [Provacel™(PUMP1)] are safe and possibly effective in the treatment of acute myocardial infarction (heart attack).

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mesoblast International Sàrl
• Last Updated: 2014-12-02

Criteria

Inclusion Criteria:

• Male or female between 21 and 85 years old

• First heart attack within 1 to 10 days

Exclusion Criteria:

• Positive for HIV 1 and 2

• Previous heart attack

• Pacemaker or other device

• Pregnant or breastfeeding

• Allergic to cow or pig derived products

• Previous bone marrow transplant

• Involved in another clinical trial within the past 30 days

• Alcohol or recreational drug abuse within the past 6 months

• Hepatitis Positive

• Major surgical procedure or major trauma within the past 14 days

• Body weight greater than 300 pounds

• Autoimmune disease ( e.g. Lupus, Multiple Sclerosis)