Safety Study & Effectiveness of Docetaxel With RAD001 and Bevacizumab in Men With Advanced Prostate Cancer
Status:
Completed
Trial end date:
2017-02-17
Target enrollment:
Participant gender:
Summary
Prostate cancer is a common and important health issue. Although effective treatment is often
available for localized disease, metastatic prostate cancer remains incurable. The initial
treatment for metastatic prostate cancer often includes medical or surgical treatments that
deprive the tumor of male hormones (androgens) required for growth. Although this treatment
is successful for many patients, the cancer may eventually return in others. Recurrent
prostate cancer may be treated with additional hormonal agents, but these agents usually do
not result in long-term control of the disease. Eventually most patients with recurrent
prostate cancer progress to a state where the cancer grows despite very low level of
circulating male hormones known as androgen independent prostate cancer (AIPC).