Overview

Safety Evaluation of 3K3A-APC in Ischemic Stroke

Status:
Completed
Trial end date:
2017-06-29
Target enrollment:
Participant gender:
Summary
The purpose of this study was to evaluate the safety, pharmacokinetics (PK) and preliminary efficacy of multiple ascending intravenous doses of 3K3A-APC, a Recombinant Variant of Human activated protein C (APC), in in the treatment of acute ischemic stroke following treatment with recombinant tissue plasminogen activator (tPA), mechanical thrombectomy or both.
Phase:
Phase 2
Details
Lead Sponsor:
ZZ Biotech, LLC
Collaborators:
Cedars-Sinai Medical Center
Massachusetts General Hospital
National Institute of Neurological Disorders and Stroke (NINDS)
University of Iowa
Treatments:
Protein C