Overview

SWOG-9304 Chemotherapy Plus Radiation Therapy in Treating Patients With Rectal Cancer That Has Been Surgically Removed

Status:
Completed
Trial end date:
2008-10-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known which treatment regimen is more effective for rectal cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of different regimens of combination chemotherapy plus radiation therapy in treating patients who have rectal cancer that has been surgically removed.
Phase:
Phase 3
Details
Lead Sponsor:
Southwest Oncology Group
Collaborators:
Cancer and Leukemia Group B
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)
NCIC Clinical Trials Group
North Central Cancer Treatment Group
Radiation Therapy Oncology Group
Treatments:
Calcium
Fluorouracil
Leucovorin
Levamisole
Levoleucovorin