STrategic Reperfusion in Elderly Patients Early After Myocardial Infarction
Status:
Recruiting
Trial end date:
2022-10-01
Target enrollment:
Participant gender:
Summary
In patients ≥ 60yrs with acute ST-elevation myocardial infarction randomised within 3 hours
of onset of symptoms the efficacy and safety of a strategy of early fibrinolytic treatment
with half-dose tenecteplase and additional antiplatelet therapy with a loading dose of 300 mg
clopidogrel, aspirin and coupled with antithrombin therapy followed by catheterisation within
6-24 hours or rescue coronary intervention as required, will be compared to a strategy of
primary PCI with a P2Y12 antagonist and antithrombin treatment according to local standards.
Phase:
Phase 4
Details
Lead Sponsor:
Katholieke Universiteit Leuven KU Leuven
Collaborators:
Boehringer Ingelheim Fund for Clinical Cardiovascular Research at LRD Life Sciences Research Partners