Overview

STS Administration on Coronavirus Disease (COVID-19) Patients in Critical Care

Status:
Recruiting
Trial end date:
2023-02-28
Target enrollment:
0
Participant gender:
All
Summary
The primary purpose is to describe the safety of administration of three doses of STS to critically ill patients with confirmed COVID-19. A secondary purpose is to describe data on the clinical efficacy of administration of up to three doses of STS in critically ill patients with confirmed COVID-19.
Phase:
Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Hellenic Institute for the Study of Sepsis
Treatments:
Sodium thiosulfate
Criteria
Inclusion Criteria:

1. Age equal to or older than 18 years

2. Both genders

3. For women of childbearing potential, they must use or be willing to use a dual
contraceptive method during the study.

4. Written consent statement provided by the patient or his / her legal representative in
case patients are unable to consent.

5. Confirmed COVID-19 disease

6. WHO-CPS 7 to 9

7. Hospitalization in Intensive Care Unit

8. Serum H2S levels less than 140 μM

Exclusion Criteria:

1. Age less than 18 years

2. Denial of written consent

3. Decision not to resuscitate