SMOOTH - Blood Pressure Control in Diabetic/Obese Patients
Status:
Completed
Trial end date:
2004-12-01
Target enrollment:
Participant gender:
Summary
The primary objective of this study is to demonstrate that telmisartan 80 mg combined with
hydrochlorothiazide 12.5 mg (T80/H12.5) is at least as effective and possibly superior to
valsartan 160 mg combined with hydrochlorothiazide 12.5 mg (V160/H12.5) in lowering mean
ambulatory systolic blood pressure (SBP) and diastolic blood pressure (DBP) during the last 6
hours of the 24-hour dosing interval at the end of a 10-week treatment period in
mild-to-moderate hypertensive, overweight or obese patients with type 2 diabetes mellitus