SLOS: The Effect of Simvastatin in Patients Receiving Cholesterol Supplementation

• Status: Terminated
• Trial end date: 2014-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine if simvastatin improves development and behavior in patients with Smith Lemli-Opitz syndrome (SLOS) receiving dietary cholesterol supplementation.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Oregon Health and Science University
• Collaborator: National Heart, Lung, and Blood Institute (NHLBI)
• Treatments: Simvastatin

Criteria

Inclusion Criteria:

• Male or female over 1 years old

• Subject has confirmed diagnosis of Smith-Lemli-Opitz Syndrome

• Subject is currently receiving cholesterol supplementation

Exclusion Criteria:

• Subjects too ill to travel to the study site

• Subjects who are unable to safely undergo study procedures

• Pregnant women