SLIM: Combined Effects of Slo-Niacin and Atorvastatin on Lipoproteins and Inflammatory Markers in Hyperlipidemia

• Status: Completed
• Trial end date: 2006-01-01
• Target enrollment: 0
• Participant gender: All

Summary

Slo-Niacin and atorvastatin (Lipitor) are both drugs that lower cholesterol. In this research, we will compare the effectiveness of Slo-Niacin and atorvastatin taken alone and together. This study will help show how the individual benefits of the two drugs taken separately can be combined when taken together.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Washington
• Collaborator: Upsher-Smith Laboratories
• Treatments: Atorvastatin; Atorvastatin Calcium; Niacin; Niacinamide; Nicotinic Acids

Criteria

Inclusion Criteria:

• LDL-C > 130 mg/dL

• HDL-C <= 45 mg/dL in men and <= 55 mg/dL in women

Exclusion Criteria:

• history of hypersensitivity to any statin, niacin or aspirin

• diagnosis of diabetes or a fasting glucose > 125 mg/dL

• hyper or hypothyroidism (unless treatment stable)

• meet other health, medication, and logistical criteria