SHIELD Study: Using Naso-oropharyngeal Antiseptic Decolonization to Reduce COVID-19 Viral Shedding
Status:
Recruiting
Trial end date:
2022-04-30
Target enrollment:
Participant gender:
Summary
Essential workers in positions with increased likelihood of exposure to SARS-CoC-2 will be
most impacted by the proposed project. Evidence has shown that the SARS-CoV-2 novel
coronavirus is easily transmissable through close contact between individuals, especially
during aerosol-generating procedures such as intubation of patients. The intervention
proposed in this study (nasal and oral decontamination with povidone-iodine and
chlorhexidine, respectively) presents an opportunity for a safe, effective, and feasible
treatment to decontaminate the primary entry points for SARS-CoV-2. As such, the intervention
to be studied in this project may protect healthcare and other essential workers by
preventing transmission of SARS-CoV-2 from patients to healthcare workers, as well as the
general public to essential worker,. and thus reducing the incidence of COVID-19 in these
workers.