S0230 Goserelin in Preventing Ovarian Failure in Women Receiving Chemotherapy for Breast Cancer
Status:
Completed
Trial end date:
2016-09-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Goserelin blocks hormone production in the ovaries. It is not yet known whether
ovarian suppression using goserelin will prevent ovarian failure (early menopause) in women
receiving chemotherapy for breast cancer.
PURPOSE: This randomized phase III trial is studying how well giving goserelin together with
chemotherapy works compared with chemotherapy alone in preventing early menopause in women
with stage I, stage II, or stage IIIA breast cancer.
Phase:
Phase 3
Details
Lead Sponsor:
Southwest Oncology Group
Collaborators:
Cancer and Leukemia Group B Eastern Cooperative Oncology Group International Breast Cancer Study Group National Cancer Institute (NCI)