Overview

Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic Leukemia

Status:
Recruiting
Trial end date:
2024-09-05
Target enrollment:
Participant gender:
Summary
This study will test if adding ruxolitinib to standard multi-drug chemotherapy regimen will be safe and tolerated in adolescents and young adults with newly diagnosed Ph-like acute lymphoblastic leukemia (ALL).
Phase:
Phase 1
Details
Lead Sponsor:
University of Chicago
Collaborator:
Incyte Corporation
Treatments:
6-Mercaptopurine
Cyclophosphamide
Cytarabine
Dexamethasone
Doxorubicin
Mercaptopurine
Methotrexate
Pegaspargase
Rituximab
Thioguanine
Vincristine