Overview

Rucaparib and Irinotecan in Cancers With Mutations in DNA Repair

Status:
Completed
Trial end date:
2021-03-01
Target enrollment:
Participant gender:
Summary
This is an open label, non-randomized, dose escalation and expansion Phase Ib trial to evaluate the safety and recommended phase II dose of the combination of irinotecan and rucaparib.
Phase:
Phase 1
Details
Lead Sponsor:
Pamela Munster
Collaborator:
Clovis Oncology, Inc.
Treatments:
Camptothecin
Irinotecan
Poly(ADP-ribose) Polymerase Inhibitors
Rucaparib