Routine Use of Antiretroviral Therapy to Prevent Mother-to-Child HIV Transmission in the Kafue District of Zambia
Status:
Completed
Trial end date:
2012-01-01
Target enrollment:
Participant gender:
Summary
The investigators will enroll a cohort of HIV-infected pregnant women accessing PMTCT
services, to better understand the incremental benefits (e.g. reduction in HIV transmission,
improvements in HIV-free survival) and risks (e.g. drug toxicities) of the routine HAART
strategy, in comparison to HIV-infected pregnant women accessing the Zambian Standard of Care
services.
The investigators will test the hypothesis that routine use of HAART produces significant
reductions in HIV transmission rates, with only minimal side effects.