Ropivacaine Continuous Wound Infusion Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Delivery
Status:
Completed
Trial end date:
2018-06-29
Target enrollment:
Participant gender:
Summary
Cesarean delivery is one of the most common surgical procedures, performed at an increasingly
high rate. It is associated with intense postoperative pain that may hamper the
rehabilitation process and interfere with patient satisfaction and care provided to the
newborn. Therefore, control of perioperative pain with multimodal regimens using local
anesthetic may be important in short- and long-term convalescence after surgery.
Opioid-based regimens are the "gold standard" of cesarean delivery analgesia. However, spinal
and epidural opioids have a ceiling effect.
Wound infiltration with local anesthetics has been used widely in the multimodal approach of
pain relief. Continuous wound infusion with local anesthetic through a multiorifice catheter
increases the duration of action and efficacy of local surgical wound infiltration compared
with a one-time wound injection of local anesthetic.
After cesarean delivery, Local anesthetic continuous wound infusion would be associated with
better reduction in pain scores when compared to intrathecal morphine . Therefore, an
assessor and patient blinded, randomized study that aimed to compare the efficacy and side
effects of these analgesia techniques was conducted.