Role of Vitamin C to Augment Iron Chelation With DFP or DFX

• Status: Unknown status
• Trial end date: 2014-04-01
• Target enrollment: 0
• Participant gender: All

Summary

role of Vit C to Augment iron chelation with DFP or DFX in thalassemic patients.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University
• Treatments: Ascorbic Acid; Chelating Agents; Deferiprone; Iron; Vitamins

Criteria

Inclusion Criteria:

• • Subjects with overload secondary to thalassemia major

Exclusion Criteria:

• • with HIV positive or have active HCV.

• A history of serious immunologic hypersensitivity to any medication such as anaphylaxis or angioedema.

• Participation in a previous investigational drug study within the 30 days preceding screening.

• A woman of childbearing potential must have a negative serum pregnancy test at screening. She must use a medically acceptable form of birth control during the study and for a month afterwards who are pregnant or breast-feeding.

• An inability to adhere to the designated procedures and restrictions of this protocol.