Role of Sympathetic Activation in Ischemia Reperfusion Injury
Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
This study is designed to assess the effect of forearm ischemia-reperfusion injury on
sympathetic nerve activity. To determine whether reduced sympathetic responsiveness is a
contributor to the protective effects of remote ischemic preconditioning. In addition it will
assess whether pharmacologic inhibition of the sympathetic nervous system can ameliorate
ischemia reperfusion injury induced endothelial dysfunction.