Role of Serotonin in Acute and Subacute MDMA Effects
Status:
Completed
Trial end date:
2011-08-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to measure the effects of MDMA (particularly its emotional
effects) and to determine the role of serotonin in these effects. Serotonin is a
neurotransmitter, which is a chemical that is released by some brain cells to communicate
with other brain cells. Many of the effects of MDMA are thought to be the result of increased
serotonin release.
In order to understand the effects of MDMA and role of serotonin in these effects, we will
administer MDMA alone and in combination with the antidepressant citalopram (one trade name
for this is Celexa). Citalopram decreases the ability of MDMA to release serotonin.
Citalopram will therefore decrease any of MDMA's effects that are the result of serotonin
release; we want to measure this.
Phase:
N/A
Details
Lead Sponsor:
California Pacific Medical Center Research Institute