Role of Saffron and Chamomile in the Management of Parkinson's Disease
Status:
Recruiting
Trial end date:
2023-07-01
Target enrollment:
Participant gender:
Summary
In multitudinous preclinical studies, Saffron and Chamomile are found effective in treating
PD. They can mitigate the neurodegenerative progression of the disease by curtailing
dopaminergic and neuronal loss and by inhibiting alpha-synuclein aggregation. They also
possess antioxidant and anti-inflammatory activities. The synergism of both drugs can manage
Parkinson's disease and related neurological disorders although, clinical trials are needed
for further elaboration. Therefore, the purpose of the study is to evaluate the effects of
Saffron and Chamomile and their active compounds in treating Parkinson's disease. This
combination may change psychometric measures (MDS-Unified Parkinson's Disease Rating Scale),
biomarkers (including Alpha-synuclein), and oxidative stress-related to Parkinson's disease.
This combination along with conventional therapy might be beneficial in managing patients
with Parkinson's disease
Phase:
N/A
Details
Lead Sponsor:
Jinnah Postgraduate Medical Centre
Collaborators:
Aga Khan University Hospital, Pakistan Liaquat National Hospital & Medical College