Role of Propranolol as Compared to Bleomycin in Management of Hemangioma
Status:
Completed
Trial end date:
2018-01-01
Target enrollment:
Participant gender:
Summary
Infantile hemangiomas are widespread vascular tumours having incidence of 10% and most of
them involute spontaneously. However, they are known to be located in proximity of vital
organs and can have poor cosmetic and functional sequel if left untreated. A wide range of
treatment options are available from expectant therapy to radical surgical excision.
Propanolol has also been shown to be effective in treating infantile cutaneous hemangiomas.
Similarly, anti-metabolite drugs as bleomycin has also shown promising results. Efficacy in
terms of reduction in size of both treatments has been scarcely studied especially in
Pakistan.
OBJECTIVE: To assess the efficacy of oral propranolol and intraleisonal bleomycin in the
treatment of infantile cutaneous hemangioma in terms of size regression