Role of Pregabalin in Treatment of Post-Op Pain in Fracture Patients

• Status: Completed
• Trial end date: 2009-08-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a randomized, prospective, double-blind pilot study designed to evaluate the potential effectiveness of pregabalin in post-operative pain management for patients who have sustained a fracture.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Alabama at Birmingham
• Collaborator: Pfizer
• Treatments: Pregabalin

Criteria

Inclusion Criteria:

• fractures requiring operative treatment during a single operative episode

• Adult patients between the ages of 19 and 70

Exclusion Criteria:

• prior medical history of narcotic abuse or narcotic use within 2 weeks of injury (except those given in hospital)

• contraindications to pregabalin or narcotic analgesics

• significant closed head injury

• psychiatric illness requiring medical treatment

• surgery for other injuries (splenectomy, etc)

• history of seizures requiring current anticonvulsant therapy

• inability or unwillingness to give informed consent