Role of N-Acetylcysteine in Treatment of Bacterial Vaginosis
Status:
Unknown status
Trial end date:
2013-06-01
Target enrollment:
Participant gender:
Summary
N-Acetyl cysteine (NAC) is an amino acid with strong antioxidant, mucolytic and antibacterial
properties, and is produced within the human body.Its effect in biofilms has been tested in
several bacteria. Biofilms have recently been observed in 90% of subjects with bacterial
vaginosis (BV) with Gardnerella vaginalis being the predominant species. Although a wide
range of antimicrobial agents are currently available, treatment options for controlling BV
are still limited. Furthermore, the number of relapses are increasing and require alternative
treatments. This study is aiming to evaluate the role of NAC in treatment of BV and
prevention of recurrence.