Role of Montelukast in the Management of Chronic Rhinosinusitis With Nasal Polyps.

• Status: Not yet recruiting
• Trial end date: 2024-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the work is to examine the efficacy of montelukast as an adjunct to steroid therapy in patients with chronic rhinosinusitis with nasal polyps.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Fluticasone; Montelukast; Prednisolone; Xhance

Criteria

Inclusion Criteria:

• - 1- Adult patients (aged 18 years and over)

• 2- Bilateral denovo nasal polyps confirmed by nasal endoscopy and CT scan.

Exclusion Criteria:

• - 1- CRS patients without nasal polyposis.

• 2- Patient with unilateral nasal polyp.

• 3- Revision cases (history of previous surgical treatment).

• 4- Patient with fungal rhinosinusitis..

• 5- Pregnancy and lactation.

• 6- Malignancies.